Imposter Zoster: An Atypical Case of Varicella-Zoster Virus Infection

Cureus. 2023 Jul 18;15(7):e42104. doi: 10.7759/cureus.42104. eCollection 2023 Jul.

Abstract

In this report, we describe a case involving an 80-year-old female who presented to the emergency department with an acute onset of left upper quadrant abdominal pain. The chief complaint misled us down multiple pathways of considering ischemic bowel disease, peptic ulcer disease, and small bowel obstruction. As a result, this led to costly and invasive diagnostic studies. However, the actual cause eventually became apparent - a cutaneous varicella-zoster virus infection. This case underscores the significance of maintaining a comprehensive list of potential diagnoses, particularly in elderly adults who commonly present atypically and often face difficulty expressing their symptoms. It also underlines the diagnostic challenges associated with identifying shingles without cutaneous findings. Early detection is crucial in preventing unnecessary tests, minimizing costs, and avoiding treatment delays. Furthermore, the case is a powerful example of the importance of vaccination, which has been proven to be 68-97% effective in preventing shingles and postherpetic neuralgia, depending on the individual's immune function.

Keywords: abdominal pain; antivirals; geriatrics; high-value care; polymerase chain reaction; postherpetic neuralgia; shingles; vaccination; varicella zoster; visceral pain.

Publication types

  • Case Reports