Microbiologist in the clinic: coitally related symptoms with negative urine cultures

Int Urogynecol J. 2023 Nov;34(11):2701-2704. doi: 10.1007/s00192-023-05662-7. Epub 2023 Oct 14.

Abstract

In this first episode of the Microbiologist in the Clinic series, clinicians and laboratory scientists share their perspectives about a 30 y/o woman, who is seeking specialty consultation for frequent episodes of urinary urgency, frequency, and dysuria, which respond to short courses of antibiotics. Although her home dipsticks suggest that she has a UTI, and her urinalysis typically has a moderate number of white blood cells, her urine cultures are always negative. The challenges of this clinical presentation are discussed with evidence for evaluation and treatment.

Keywords: Antibiotics; Lower Urinary Tract Symptoms; Microbiome; Pyuria; UTI; Urobiome; Women’s Health.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Dysuria
  • Female
  • Humans
  • Urinalysis
  • Urinary Tract Infections* / diagnosis
  • Urinary Tract Infections* / drug therapy
  • Urination Disorders*
  • Urine

Substances

  • Anti-Bacterial Agents