1 Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
2 Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, North Carolina, USA.
3 University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
4 Multidisciplinary Center for Inflammatory Bowel Diseases, University of North Carolina, Chapel Hill, North Carolina, USA.
5 Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.