Life-Threatening Electrical Storm Following Liver Transplantation: A Case Report

Am J Case Rep. 2024 Jan 5:25:e941932. doi: 10.12659/AJCR.941932.

Abstract

BACKGROUND Electrical storm is a rare but potentially life-threatening syndrome characterized by recurrent ventricular arrhythmias. Liver transplant recipients are at increased risk of developing electrical storms due to conditions that prolong QT intervals, such as cirrhotic cardiomyopathy. However, limited information exists on electrical storms in this specific population. This case report presents a patient who experienced 13 cardiac arrests during ventricular fibrillation following liver transplantation. CASE REPORT A 61-year-old woman with a medical history of diabetes, obesity, and cirrhosis due to non-alcoholic fatty liver disease underwent liver transplantation using a deceased donor's liver. Following the procedure, she developed a deterioration in her respiratory function, necessitating orotracheal intubation. Approximately 21 hours post-surgery, she experienced cardiac arrest during ventricular fibrillation, which was rapidly reversed with electrical defibrillation. However, the patient entered a state of electrical storm. Management involved antiarrhythmic medications and temporary transvenous cardiac pacing. She remained stable for 40 hours, but a dislodgment of the device triggered another episode of ventricular fibrillation, leading to her death. CONCLUSIONS This case report highlights the clinical presentation and challenges in managing electrical storms in liver transplant recipients. We hypothesize that cirrhotic cardiomyopathy could be the cause of her recurrent ventricular arrhythmias. Further studies are needed to better understand the underlying mechanisms and risk factors of this life-threatening syndrome in this population, which may enhance risk stratification and enable earlier intervention.

Publication types

  • Case Reports

MeSH terms

  • Arrhythmias, Cardiac / etiology
  • Cardiomyopathies* / complications
  • Female
  • Heart Arrest* / complications
  • Heart Arrest* / therapy
  • Humans
  • Liver Cirrhosis / complications
  • Liver Transplantation* / adverse effects
  • Middle Aged
  • Ventricular Fibrillation / complications
  • Ventricular Fibrillation / therapy