Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

Affiliations

• ¹ Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.
• ² Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
• ³ Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MD, USA; UCL Cancer Institute, University College London, London, UK.
• ⁴ The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
• ⁵ Division of Cardiovascular Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK.
• ⁶ The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
• ⁷ Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
• ⁸ Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute, Cambridge, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
• ⁹ Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
• ¹⁰ Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
• ¹¹ Division of Nephrology and Hypertension, Loyola University Chicago, Maywood, IL, USA.
• ¹² Population Health Research Institute, Hamilton, ON, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
• ¹³ Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
• ¹⁴ Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
• ¹⁵ Unidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
• ¹⁶ John P Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
• ¹⁷ The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA.
• ¹⁸ Missouri Breaks Industries Research Inc., Eagle Butte, SD, USA.
• ¹⁹ Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
• ²⁰ Division of Endocrinology and Metabolism, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
• ²¹ Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
• ²² Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
• ²³ Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.
• ²⁴ Laboratório de Genética e Cardiologia Molecular do Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
• ²⁵ Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.
• ²⁶ Division of Nephrology, Department of Medicine, University of Illinois, Chicago, IL, USA.
• ²⁷ Center for Clinical and Epidemiological Research, Hospital Universitário, Universidade de São Paulo (USP), São Paulo, Brazil.
• ²⁸ The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
• ²⁹ Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, CA, USA.
• ³⁰ Department of Pediatrics, Genetic and Genomic Medicine, University of California, Irvine, Irvine, CA, USA.
• ³¹ Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
• ³² Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
• ³³ Departamento de Genética, Ecologia e Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
• ³⁴ MedStar Health Research Institute, Hyattsville MD and Georgetown-Howard Universities Center for Clinical and Translational Science, Washington, DC, USA.
• ³⁵ University of Washington School of Medicine, Seattle, WA, USA; Office of Healthcare Equity, UW Justice, Equity, Diversity, and Inclusion Center for Transformational Research (UW JEDI-CTR), University of Washington, Seattle, WA, USA; Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA, USA; Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA, USA.
• ³⁶ Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute, Cambridge, MA, USA.
• ³⁷ Center for American Indian Health Research, Department of Biostatistics and Epidemiology, Hudson College of Public Health, The University of Oklahoma Health Sciences Center, Oklahoma, OK, USA.
• ³⁸ Department of Neurology, Epidemiology and Public Health, Miller School of Medicine, University of Miami, Miami, FL, USA.
• ³⁹ Brown Foundation Institute of Molecular Medicine, Houston, TX, USA.
• ⁴⁰ Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil.
• ⁴¹ Laboratório de Genética e Cardiologia Molecular do Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Aging Division, Brigham Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA.
• ⁴² Texas Biomedical Research Institute, San Antonio, TX, USA.
• ⁴³ Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
• ⁴⁴ National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
• ⁴⁵ School of Science, Psychology and Sport, Federation University, Ballarat, VIC, Australia; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; Department of Physiology, University of Melbourne, Melbourne, VIC, Australia.
• ⁴⁶ Division of Cardiovascular Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK; Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
• ⁴⁷ Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK. Electronic address: [email protected].
• ⁴⁸ Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: [email protected].