Osteopontin is associated with neutrophil extracellular trap formation in elderly patients with severe sepsis

Eur J Clin Invest. 2024 Apr;54(4):e14159. doi: 10.1111/eci.14159. Epub 2024 Jan 24.

Maria Bertolotto¹, Daniela Verzola¹, Paola Contini^{1

2}, Daniela de Totero³, Amedeo Tirandi¹, Davide Ramoni¹, Stefano Ministrini⁴, Daniele Roberto Giacobbe^{2

5}, Aldo Bonaventura⁶, Alessandra Vecchié⁶, Luca Castellani², Michele Mirabella², Eleonora Arboscello², Luca Liberale^{1

7}, Francesca Viazzi^{2

8}, Matteo Bassetti^{2

5}, Fabrizio Montecucco^{1

7}, Federico Carbone^{1

7}

¹ Department of Internal Medicine, University of Genoa, Genoa, Italy.
² IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
³ Molecular Pathology Unit IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
⁴ Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.
⁵ Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
⁶ Medicina Generale 1, Medical Center, Ospedale di Circolo e Fondazione Macchi, ASST Sette Laghi, Varese, Italy.
⁷ IRCCS Ospedale Policlinico San Martino Genoa, Italian Cardiovascular Network, Genoa, Italy.
⁸ Clinic of Nephrology, Department of Internal Medicine, University of Genoa, Genoa, Italy.

No abstract available

Keywords: Inflammation; neutrophil extracellular traps; osteopontin; sepsis.

Publication types