De novo accelerated phase of chronic myeloid leukemia should be recognized even in the era of tyrosine kinase inhibitors

Tomas Hornak; Jiri Mayer; Petra Cicatkova; Lukas Semerad; Anezka Kvetkova; Hana Klamova; Edgar Faber; Petra Belohlavkova; Michal Karas; Lukas Stejskal; Eduard Cmunt; Olga Cerna; Dana Srbova; Hana Zizkova; Lucia Vrablova; Ivana Skoumalova; Jaroslava Voglova; Tereza Jurkova; Marika Chrapava; Tomas Jurcek; Ivana Jeziskova; Marie Jarosova; Katerina Machova Polakova; Tomas Papajik; Pavel Zak; Pavel Jindra; Daniela Zackova

doi:10.1002/ajh.27229

De novo accelerated phase of chronic myeloid leukemia should be recognized even in the era of tyrosine kinase inhibitors

Am J Hematol. 2024 Apr;99(4):763-766. doi: 10.1002/ajh.27229. Epub 2024 Feb 5.

Authors

Tomas Hornak¹, Jiri Mayer^{1

2}, Petra Cicatkova¹, Lukas Semerad¹, Anezka Kvetkova¹, Hana Klamova³, Edgar Faber⁴, Petra Belohlavkova⁵, Michal Karas⁶, Lukas Stejskal^{7

8}, Eduard Cmunt⁹, Olga Cerna¹⁰, Dana Srbova³, Hana Zizkova³, Lucia Vrablova⁴, Ivana Skoumalova⁴, Jaroslava Voglova⁵, Tereza Jurkova¹¹, Marika Chrapava¹¹, Tomas Jurcek¹, Ivana Jeziskova¹, Marie Jarosova¹, Katerina Machova Polakova³, Tomas Papajik⁴, Pavel Zak⁵, Pavel Jindra⁶, Daniela Zackova¹

Affiliations

¹ Dpt. of Internal Medicine Hematology and Oncology, University Hospital Brno and Masaryk University, Brno, Czech Republic.
² Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
³ Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
⁴ Dpt. of Hemato-oncology, University Hospital Olomouc and Palacky University, Olomouc, Czech Republic.
⁵ 4th Dpt. of Internal Medicine and Hematology, University Hospital Hradec Kralove and Charles University, Hradec Kralove, Czech Republic.
⁶ Dpt. of Hemato-oncology, University Hospital Pilsen and Charles University, Pilsen, Czech Republic.
⁷ Dpt. of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic.
⁸ Dpt. of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.
⁹ 1st. Internal Dpt, General University Hospital Prague, Prague, Czech Republic.
¹⁰ Dpt. of Hematology, University Hospital Kralovske Vinohrady and Charles University, Prague, Czech Republic.
¹¹ Institute of Biostatistics and Analyses, Brno, Czech Republic.

PMID: 38317312
DOI: 10.1002/ajh.27229

Abstract

Overall survival of patients classified according to the European LeukemiaNet 2020 classification. Chronic phase (CP), accelerated phase (AP), blast crisis (BC), low risk (LR), intermediate risk (IR), high risk (HR).

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Blast Crisis / drug therapy
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / drug therapy
Protein Kinase Inhibitors / therapeutic use
Tyrosine Kinase Inhibitors*

Substances

Tyrosine Kinase Inhibitors
Protein Kinase Inhibitors

Abstract

Publication types

MeSH terms

Substances

Grants and funding