A multicenter study of maternal conditions and amniotic fluid volume in Ethiopia in 2023

Physiol Rep. 2024 Mar;12(6):e15994. doi: 10.14814/phy2.15994.

Abstract

The amniotic fluid is a protective liquid found in amniotic found in the amniotic sac and mainly containing water and some solid substances including epitheloid and fibroblastic type cells. Most of the studies conducted about amniotic fluid volume (AFV) reported fetal and placental factors as a determinant of AFV. The aim of this study is to examine maternal and obstetric conditions in relation to AFV among women with term pregnancies. A multicenter institutional based cross-sectional study was conducted among clients attending selected public hospitals of South Gondar Zone, Ethiopia from January 01, 2023 to May 30, 2023. The sample size was calculated by using the assumption of single population proportion formula considering the prevalence value of 50%, 95% confidence interval, and margin of error 5% and 10% non respondent rate. In our study rural residency AOR = 3.21 (1.19-5.37), chronic illness AOR = 2.12 (1.33-4.61), short inter pregnancy interval AOR = 3.03 (2.18-6.28), Hypermesis gravidarum AOR = 1.19 (1.02-4.41), and maternal diabetics AOR = 2.16 (1.32-4.75) had significant association with the outcome variable. These maternal conditions may be correlated with an abnormal volume of amniotic fluid.

Keywords: Ethiopia; amniotic fluid; maternal condition; oligohydramnios; polyhydramnios.

Publication types

  • Multicenter Study

MeSH terms

  • Amniotic Fluid*
  • Cross-Sectional Studies
  • Ethiopia / epidemiology
  • Female
  • Humans
  • Oligohydramnios*
  • Placenta
  • Pregnancy