Intratumoral heterogeneity of CDKN2A deletions in IDH-mutant astrocytoma

Brain Tumor Pathol. 2024 Apr;41(2):92-95. doi: 10.1007/s10014-024-00484-x. Epub 2024 Apr 10.
No abstract available

Keywords: CDKN2A; FISH; IDH-mutant astrocytoma; Intratumoral heterogeneity; Somatic mosaicism.

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Adult
  • Astrocytoma* / genetics
  • Astrocytoma* / pathology
  • Brain Neoplasms* / genetics
  • Brain Neoplasms* / pathology
  • Cyclin-Dependent Kinase Inhibitor p16* / genetics
  • Gene Deletion
  • Humans
  • Isocitrate Dehydrogenase* / genetics
  • Male
  • Mutation*

Substances

  • CDKN2A protein, human
  • Cyclin-Dependent Kinase Inhibitor p16
  • IDH1 protein, human
  • Isocitrate Dehydrogenase