Visual vertigo and motion sickness is different between persistent postural-perceptual dizziness and vestibular migraine

Am J Otolaryngol. 2024 Jul-Aug;45(4):104321. doi: 10.1016/j.amjoto.2024.104321. Epub 2024 Apr 21.

Abstract

Introduction: Persistent postural-perceptual dizziness (PPPD) and vestibular migraine (VM) share symptoms of visual vertigo and motion sickness that can be confusing for clinicians to distinguish. We compare the severity of these symptoms and dynamic subjective visual vertical (dSVV) in these two common vestibular conditions.

Method: Twenty-nine patients with PPPD, 37 with VM, and 29 controls were surveyed for subjective symptoms using the visual vertigo analogue scale (VVAS) and motion sickness susceptibility questionnaire during childhood (MSA) and the past 10 years (MSB). dSVV is a measure of visual dependence measures perception of verticality against a rotating background (5 deg./s).

Results: VVAS revealed contextual differences for dizziness between those with PPPD and VM. Ratings of visual vertigo were most severe in PPPD, less in VM, and mild in controls (VVAS PPPD 27.1, VM 11.2, control 4.6, p < 0.001). MSA was more severe in VM than in PPPD or control (12.8 vs 7.6 vs 8.5, p = 0.01). MSB was more severe in VM than controls (MSB score 12.9 VS 8.1 p = 0.009) but was not different than PPPD (MSB score 10.0, p = 0.10). dSVV alignment was similar among the three groups (p = 0.83). Both VM and PPPD groups had greater simulator sickness than controls after completing the dSVV.

Conclusions: Patients with PPPD report more visual vertigo than those with VM, but a history of motion sickness as a child is more common in VM. Additionally, the environmental context that induces visual vertigo is different between PPPD and VM.

Keywords: Motion sickness; Persistent postural-perceptual dizziness; Subjective visual vertical; Vestibular migraine; Vestibular rehabilitation; Visual vertigo.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Dizziness* / diagnosis
  • Dizziness* / etiology
  • Dizziness* / physiopathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Migraine Disorders* / complications
  • Migraine Disorders* / diagnosis
  • Migraine Disorders* / physiopathology
  • Motion Sickness* / complications
  • Motion Sickness* / physiopathology
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Vertigo* / diagnosis
  • Vertigo* / physiopathology