Pioneering nanomedicine in orthopedic treatment care: a review of current research and practices

Front Bioeng Biotechnol. 2024 May 27:12:1389071. doi: 10.3389/fbioe.2024.1389071. eCollection 2024.

Abstract

A developing use of nanotechnology in medicine involves using nanoparticles to administer drugs, genes, biologicals, or other materials to targeted cell types, such as cancer cells. In healthcare, nanotechnology has brought about revolutionary changes in the treatment of various medical and surgical conditions, including in orthopedic. Its clinical applications in surgery range from developing surgical instruments and suture materials to enhancing imaging techniques, targeted drug delivery, visualization methods, and wound healing procedures. Notably, nanotechnology plays a significant role in preventing, diagnosing, and treating orthopedic disorders, which is crucial for patients' functional rehabilitation. The integration of nanotechnology improves standards of patient care, fuels research endeavors, facilitates clinical trials, and eventually improves the patient's quality of life. Looking ahead, nanotechnology holds promise for achieving sustained success in numerous surgical disciplines, including orthopedic surgery, in the years to come. This review aims to focus on the application of nanotechnology in orthopedic surgery, highlighting the recent development and future perspective to bridge the bridge for clinical translation.

Keywords: bone regeneration; nanoparticle; nanotechnology; orthopaedic surgery; orthopedic.

Publication types

  • Review

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work was supported by Public Technology Applied Research Projects of Zhejiang Province (LGF22H060023 to WL), Medical and Health Research Project of Zhejiang Province (2023KY1303 to HL, 2022ZB382 to WL), Traditional Chinese Medicine Science and Technology Projects of Zhejiang Province (2022ZB380 to JZ, 2022ZB382 to WL, 2022ZB380 to JZ), Science and Technology Project of Zhoushan (2022C31034 to CZ, 2023C31020 to LL, 2023C31019 to HeZ), Research Fund Projects of The Affiliated Hospital of Zhejiang Chinese Medicine University (2021FSYYZY45 to WL).