Patient-reported outcomes and experiences of migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite treatment dispensation: the 'ASAP' study

AIDS Res Ther. 2024 Jun 18;21(1):40. doi: 10.1186/s12981-024-00632-5.

Abstract

Background: Scholars recommend providing migrants living with HIV (MLWH) with free treatment, rapidly, once linked to care to optimize their HIV-related experiences and health outcomes. Quantitative evaluations of patient-reported measures for MLWH in such models are necessary to explore the viability of these recommendations.

Methods: Within a 96-week prospective cohort study at a multidisciplinary HIV clinic, participants received bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) for free and rapidly following care linkage. Eight patient-reported measures were administered at weeks 4, 24, and 48: (1) mMOS-SS to measure perceived social support; (2) IA-RSS to measure internalized stigma; (3) K6 to measure psychological distress; (4) PROMIS to measure self-efficacy with treatment taking; (5) G-MISS to measure perceived compliance with clinicians' treatment plans; (6) HIVTSQ to measure treatment satisfaction; (7) CARE to measure perceived provider empathy; and (8) PRPCC to measure perceived clinician cultural competence. Linear mixed modelling with bootstrapping was conducted to identify significant differences by sociodemographics and time.

Results: Across weeks 4, 24, and 48, results suggest that MLWH enrolled in this study experienced moderate levels of social support; elevated levels of HIV-related stigma; moderate levels of distress; high self-efficacy with daily medication self-management; great compliance with clinicians' treatment plans; high treatment satisfaction; high perceived empathy; and high perceived cultural competence. Experience of social support (i.e., mMOS-SS scores) differed significantly by birth region. Experience of HIV-related stigma (i.e., IA-RSS scores) differed significantly by birth region, age, and language. Experience of distress (i.e., K6 scores) differed significantly by sexual orientation. Experience of treatment satisfaction (i.e., HIVTSQ scores) differed significantly by birth region and age. No significant differences were identified by time for any measure.

Conclusion: Overall, participants expressed positive experiences around treatment and care, alongside comparably lower perceptions of social support, internalized stigma, and distress, potentially underscoring a need to embed targeted, well-funded, and accessible mental health support within HIV care models.

Keywords: Care experience; HIV; Migrants; Multidisciplinary; Patient-reported outcomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Amides
  • Anti-HIV Agents* / therapeutic use
  • Drug Combinations
  • Emtricitabine / therapeutic use
  • Female
  • HIV Infections* / drug therapy
  • HIV Infections* / psychology
  • Heterocyclic Compounds, 3-Ring
  • Heterocyclic Compounds, 4 or More Rings / therapeutic use
  • Humans
  • Male
  • Medication Adherence
  • Middle Aged
  • Patient Reported Outcome Measures*
  • Patient Satisfaction
  • Piperazines / therapeutic use
  • Prospective Studies
  • Pyridones / therapeutic use
  • Self Efficacy
  • Social Stigma*
  • Social Support
  • Tenofovir / therapeutic use
  • Transients and Migrants*
  • Young Adult

Substances

  • Anti-HIV Agents
  • bictegravir
  • Heterocyclic Compounds, 4 or More Rings
  • Tenofovir
  • Emtricitabine
  • Piperazines
  • Pyridones
  • Drug Combinations
  • Amides
  • Heterocyclic Compounds, 3-Ring