Noninvasive Assessment of Portal Hypertension

Clin Liver Dis. 2024 Aug;28(3):401-415. doi: 10.1016/j.cld.2024.03.010. Epub 2024 May 8.

Abstract

The progressive use of noninvasive tests (NITs) has changed the way hepatologists diagnose and manage patients with chronic liver disease, mainly because of their easiness to use and the ability to be repeated during follow-up. Liver stiffness measurement is the NIT with more scientific evidence. NITs have demonstrated to be useful to detect not only liver fibrosis but also the presence of clinically significant portal hypertension. Moreover, current evidence supports they can also be useful to evaluate the prognosis of patients with chronic liver disease.

Keywords: Compensated advanced chronic liver disease; Liver stiffness; Noninvasive tests; Prognosis; Spleen stiffness; Transient elastography.

Publication types

  • Review

MeSH terms

  • Elasticity Imaging Techniques*
  • Esophageal and Gastric Varices / diagnosis
  • Esophageal and Gastric Varices / etiology
  • Humans
  • Hypertension, Portal* / diagnosis
  • Hypertension, Portal* / etiology
  • Hypertension, Portal* / physiopathology
  • Liver / diagnostic imaging
  • Liver / pathology
  • Liver / physiopathology
  • Liver Cirrhosis* / complications
  • Liver Cirrhosis* / diagnosis
  • Liver Cirrhosis* / physiopathology
  • Prognosis