COVID-19 causes the opening of the mitochondrial permeability transition pore in human endothelial cells

Vascul Pharmacol. 2024 Jun:155:107349. doi: 10.1016/j.vph.2024.107349.

Authors

Jessica Gambardella¹, Stanislovas S Jankauskas², Urna Kansakar², Fahimeh Varzideh², Roberta Avvisato¹, Gaetano Santulli¹

Affiliations

¹ Department of Cardiology and Molecular Pharmacology, Albert Einstein College of Medicine, Wilf Family Cardiovasc Research Institute, New York City, NY 10461, USA; Department of Advanced Biomedical Science, University of Naples Federico II, 80131 Naples, Italy.
² Department of Cardiology and Molecular Pharmacology, Albert Einstein College of Medicine, Wilf Family Cardiovasc Research Institute, New York City, NY 10461, USA.

PMID: 38985627
DOI: 10.1016/j.vph.2024.107349

No abstract available

Publication types

Letter

MeSH terms

COVID-19* / metabolism
Endothelial Cells / metabolism
Endothelial Cells / pathology
Endothelial Cells / virology
Human Umbilical Vein Endothelial Cells / metabolism
Humans
Mitochondria / metabolism
Mitochondrial Membrane Transport Proteins / metabolism
Mitochondrial Permeability Transition Pore* / metabolism
SARS-CoV-2

Substances

Mitochondrial Permeability Transition Pore
Mitochondrial Membrane Transport Proteins