Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity

Oncotarget. 2024 Jul 17:15:501-503. doi: 10.18632/oncotarget.28610.
No abstract available

Keywords: HLA-E; NKG2A; Natural killer (NK) cells; immune checkpoint blockade; immunotherapy.

Publication types

  • Editorial

MeSH terms

  • Animals
  • HLA-E Antigens*
  • Histocompatibility Antigens Class I* / immunology
  • Histocompatibility Antigens Class I* / metabolism
  • Humans
  • Killer Cells, Natural / immunology
  • NK Cell Lectin-Like Receptor Subfamily C* / immunology
  • NK Cell Lectin-Like Receptor Subfamily C* / metabolism
  • Neoplasms* / immunology
  • Neoplasms* / therapy

Substances

  • NK Cell Lectin-Like Receptor Subfamily C
  • Histocompatibility Antigens Class I
  • HLA-E Antigens
  • KLRC1 protein, human