[Current status and progress of detection methods for common clinical toxicants]

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2024 Jul 20;42(7):551-557. doi: 10.3760/cma.j.cn121094-20230609-00203.
[Article in Chinese]

Abstract

With the progress of science and technology and the development of society, more and more chemical substances have been discovered and countless chemicals have been artificially synthesized, and the risk of exposure to some toxic chemicals by human beings has been greatly increased, resulting in the increasing incidence of acute poisoning, which has seriously endangered the public's physical health and life safety. As the poisoned patients are unconscious or refuse treatment when they are admitted to the hospital, it is difficult to understand the drug exposure history by asking the medical history, so the toxicity detection has become the key to the clinical diagnosis and treatment, and this paper briefly introduces some common toxicity detection methods in the clinic in the hope that it will bring help to the clinical doctors.

随着科学技术的进步和社会的发展,越来越多的化学物质被发现,很多新的化学品被人工合成,一些有毒化学品被人类接触的风险大大增加,急性中毒发生率也日益升高,严重危害公众身体健康和生命安全。由于中毒患者入院诊治时意识不清或拒绝治疗,很难通过询问病史了解药物接触史,因此毒物检测成了临床诊治的关键,本文综述了临床一些常见毒物的检测方法,为临床医生提供参考。.

Keywords: Chromatography; Detection methods; Mass spectrometry; Poisoning; Spectrum.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Hazardous Substances*
  • Humans
  • Poisoning / diagnosis
  • Toxicity Tests / methods

Substances

  • Hazardous Substances