Characterization of the ciliary beating efficiency in primary diffuse chronic rhinosinusitis

Rhinology. 2024 Aug 8. doi: 10.4193/Rhin24.101. Online ahead of print.

Abstract

Ciliary dysfunction may result in chronic airway inflammation and infection causing injury and structural changes to the airway epithelium, leading to a variety of diseases, like bronchiectasis and primary diffuse chronic rhinosinusitis (CRS). Currently, ciliary beating analysis has mainly been studied through the measure of the ciliary beating frequency (CBF) by high-speed digital video microscopy (HSDV). However, a normal CBF has been described in different forms of primary and acquired ciliary dyskinesia.