Association of airway inflammation and smoking status with IL-33 level in sputum of patients with asthma or COPD

Eur Respir J. 2024 Sep 26;64(3):2400347. doi: 10.1183/13993003.00347-2024. Print 2024 Sep.

Abstract

In patients with COPD, targeting IL-33 might be auspicious in former smokers. However, disease severity should also be considered. In patients with severe asthma, targeting IL-33 might be a potential treatment option, irrespective of T2-status. https://bit.ly/3SFspww

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Asthma* / metabolism
  • Female
  • Humans
  • Inflammation*
  • Interleukin-33* / metabolism
  • Male
  • Middle Aged
  • Pulmonary Disease, Chronic Obstructive* / metabolism
  • Smoking*
  • Sputum* / metabolism

Substances

  • Interleukin-33
  • IL33 protein, human