Metastatic myxoid round cell liposarcoma of the buttock: a case report

Pan Afr Med J. 2024 Jun 13:48:56. doi: 10.11604/pamj.2024.48.56.40400. eCollection 2024.

Abstract

Liposarcoma is a rare primitive mesenchymal tumor, developed at the expense of adipose tissue and with a preferential location in the thigh. We report an observation of liposarcoma in the buttock. A 56-year-old man, presented with a tumor of the right buttock for 2 years. Examination revealed an inflammatory, ulcerated tumor in the upper-external quadrant of the right buttock, measuring about 8 cm. Bilateral inguinal adenopathies were associated. The diagnostic hypotheses were: a squamous cell carcinoma, a cutaneous lymphoma, and cutaneous metastases. An anatomical examination confirmed the diagnosis of myxoid round-cell liposarcoma. The extension work-up appeared compatible with secondary pleuropulmonary, hepatic, cutaneous, and lymph node neoplastic localizations. The patient was treated with chemotherapy with the Adriamycin-carboplatin protocol. The evolution was rapidly fatal after a few weeks after the first course of chemotherapy. It should be evoked in front of any ulcerated tumor of the buttock.

Keywords: Myxoid liposarcoma; buttock; case report; metastasis; round cell.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Buttocks / pathology
  • Doxorubicin / administration & dosage
  • Fatal Outcome
  • Humans
  • Liposarcoma, Myxoid* / diagnosis
  • Liposarcoma, Myxoid* / drug therapy
  • Liposarcoma, Myxoid* / pathology
  • Male
  • Middle Aged
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / pathology

Substances

  • Doxorubicin