Chronic Kidney Disease and Kidney Stone in a Wild Chimpanzee (Pan troglodytes verus) in Côte d'Ivoire

J Med Primatol. 2024 Oct;53(5):e12739. doi: 10.1111/jmp.12739.

Abstract

An older wild female chimpanzee (Pan troglodytes) was found dead with a large calcium oxalate stone in the renal pelvis. Histopathological changes included glomerulosclerosis, interstitial nephritis and fibrosis, focal mineralization, and medial hypertrophy. Urinary albumin-creatinine-ratio showed increased values from 15 months before death. Causes of the kidney disease remain unconfirmed.

Keywords: 16S; albumin‐creatinin‐ratio; calcium oxalate; microbiome; nephrolithiasis; non‐human primate; renal calculus; urinalysis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Ape Diseases* / pathology
  • Calcium Oxalate / analysis
  • Cote d'Ivoire
  • Fatal Outcome
  • Female
  • Kidney Calculi* / etiology
  • Kidney Calculi* / veterinary
  • Pan troglodytes*
  • Renal Insufficiency, Chronic* / pathology
  • Renal Insufficiency, Chronic* / veterinary

Substances

  • Calcium Oxalate