Deciphering visceral instincts: a scientific quest to unravel food choices from molecules to mind

Genes Dev. 2024 Oct 16;38(17-20):798-801. doi: 10.1101/gad.352279.124.

Abstract

The study of biological mechanisms, while crucial, cannot fully explain complex phenomena like the instinct to eat. The mind-body connection, as exemplified by the concept of "voodoo death," highlights the profound influence of belief and cultural context on physiology. Indigenous knowledge systems further emphasize the interconnectedness of humans with their environment. Recent discoveries in gut-brain communication reveal the intricate neural circuits that drive our visceral desires, but a holistic approach that integrates both physiological mechanisms and the subjective experience of life, informed by diverse cultural perspectives, will be essential to truly understand what it means to be alive.

Keywords: brain–body; physiology; symposium.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / physiology
  • Brain-Gut Axis / physiology
  • Food Preferences* / physiology
  • Humans