Cardiac MRI in Rheumatic Disease

Rheum Dis Clin North Am. 2024 Nov;50(4):735-756. doi: 10.1016/j.rdc.2024.07.010. Epub 2024 Aug 26.

Abstract

Immune-mediated systemic inflammatory disorders present a latent threat for cardiovascular disease. Early involvement may be associated with constitutional symptoms, while clinical evidence of disease may manifest later in an insidious manner. Multimodality imaging is crucial to detect myocardial involvement, with transthoracic echocardiogram as a first-line imaging modality; however, cardiac MRI (CMRI) has the potential to significantly impact our diagnostic and therapeutic approaches through high-fidelity chamber quantification and parametric mapping techniques. Novel imaging techniques are currently under investigation, including stress CMRI, feature tracking CMR, late gadolinium enhancement (LGE) entropy, and 4 dimensional flow CMRI.

Keywords: Cardiac MRI; Diastolic dysfunction; Feature tracking CMR; Four dimensional (4D) flow CMR; Late gadolinium enhancement (LGE) entropy; Myocardial fibrosis; Parametric mapping; Stress CMR.

Publication types

  • Review

MeSH terms

  • Humans
  • Magnetic Resonance Imaging* / methods
  • Magnetic Resonance Imaging, Cine / methods
  • Rheumatic Diseases / diagnostic imaging
  • Rheumatic Heart Disease / diagnostic imaging