A Core set of patient-reported outcome measures to measure quality of life in obesity treatment research

Phillip J Dijkhorst; Claire E E de Vries; Caroline B Terwee; Ignace M C Janssen; Ronald S L Liem; Bart A van Wagensveld; Johan Ottosson; Bruno Halpern; Stuart W Flint; Elisabeth F C van Rossum; Alend Saadi; Lisa West-Smith; Mary O'Kane; Jason C G Halford; Karen D Coulman; Salman Al-Sabah; John B Dixon; Wendy A Brown; Ximena Ramos Salas; Maarten M Hoogbergen; Sally Abbott; Alyssa J Budin; Jennifer F Holland; Lotte Poulsen; Richard Welbourn; Bernardo Rea Ruanova; John M Morton; Francois Pattou; Erman O Akpinar; Stephanie Sogg; Jacques M Himpens; Vanessa Osborne; Natasja Wijling; Laura Divine; Nadya Isack; Susie Birney; J M Bernadette Keenan; Joe Nadglowski; Jacqueline Bowman; Ken Clare; Riccardo Meloni; Sandra de Blaeij; Theodore K Kyle; Melanie Bahlke; Andrew Healing; Ian Patton; Valerie M Monpellier

doi:10.1111/obr.13849

A Core set of patient-reported outcome measures to measure quality of life in obesity treatment research

Obes Rev. 2024 Oct 17:e13849. doi: 10.1111/obr.13849. Online ahead of print.

Authors

Phillip J Dijkhorst¹, Claire E E de Vries², Caroline B Terwee³, Ignace M C Janssen⁴, Ronald S L Liem^{5

6}, Bart A van Wagensveld⁷, Johan Ottosson⁸, Bruno Halpern^{9

10}, Stuart W Flint^{11

12}, Elisabeth F C van Rossum^{13

14}, Alend Saadi^{15

16}, Lisa West-Smith¹⁷, Mary O'Kane¹⁸, Jason C G Halford¹¹, Karen D Coulman¹⁹, Salman Al-Sabah²⁰, John B Dixon²¹, Wendy A Brown²², Ximena Ramos Salas^{23

24}, Maarten M Hoogbergen²⁵, Sally Abbott^{26

27}, Alyssa J Budin^{22

28}, Jennifer F Holland²⁸, Lotte Poulsen^{29

30}, Richard Welbourn³¹, Bernardo Rea Ruanova³², John M Morton³³, Francois Pattou³⁴, Erman O Akpinar³⁵, Stephanie Sogg³⁶, Jacques M Himpens³⁷, Vanessa Osborne³⁸, Natasja Wijling³⁹, Laura Divine⁴⁰, Nadya Isack⁴¹, Susie Birney⁴², J M Bernadette Keenan⁴³, Joe Nadglowski⁴⁴, Jacqueline Bowman⁴⁵, Ken Clare^{41

46

47}, Riccardo Meloni⁴⁸, Sandra de Blaeij⁴⁹, Theodore K Kyle⁵⁰, Melanie Bahlke⁵¹, Andrew Healing⁴⁶, Ian Patton⁵², Valerie M Monpellier⁴

Affiliations

¹ Department of Surgery, OLVG & Dutch Obesity Clinic, Amsterdam, The Netherlands.
² Department of Surgery, OLVG, Amsterdam, The Netherlands.
³ Department of Epidemiology and Data Science, Amsterdam UMC location Vrije Universiteit, Amsterdam, The Netherlands.
⁴ Department of Science, Nederlandse Obesitas Kliniek (Dutch Obesity Clinic), Huis Ter Heide, Utrecht, The Netherlands.
⁵ Department of Surgery, Nederlandse Obesitas Kliniek (Dutch Obesity Clinic), The Hague and Gouda, Hague, The Netherlands.
⁶ Department of Surgery, Groene Hart Hospital, Gouda, The Netherlands.
⁷ Department of Surgery, NMC Royal Hospital, Abu Dhabi, United Arab Emirates.
⁸ Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
⁹ Obesity Center, 9 de Julho Hospital, São Paulo, Brazil.
¹⁰ Brazilian Association for the Study of Obesity (ABESO), São Paulo, Brazil.
¹¹ School of Psychology, University of Leeds, Leeds, UK.
¹² Scales Insights, Nexus, University of Leeds, Leeds, UK.
¹³ Obesity Center CGG, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
¹⁴ Department of Internal Medicine, Division of Endocrinology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
¹⁵ Department of Surgery, Neuchâtel Hospital, Neuchâtel, Switzerland.
¹⁶ Biology and Medicine Faculty, Lausanne University, Lausanne, Switzerland.
¹⁷ Department of Surgery, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
¹⁸ Department of Nutrition and Dietetics, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
¹⁹ National Institute for Health Research Bristol Biomedical Research Centre, and Bristol Centre for Surgical Research, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
²⁰ Department of Surgery, Kuwait University, Kuwait City, Kuwait.
²¹ Iverson Health Innovation Research Institute, Swinburne University of Technology, Melbourne, Australia.
²² Department of Surgery, Central Clinical School, Monash University, Melbourne, Australia.
²³ Obesity Canada, Edmonton, Alberta, Canada.
²⁴ European Association for the Study of Obesity, Teddington, UK.
²⁵ Department of Plastic Surgery, Catharina Hospital, Eindhoven, The Netherlands.
²⁶ Specialist Weight Management Service, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
²⁷ Research Centre for Intelligent Healthcare, Coventry University, Coventry, UK.
²⁸ Bariatric Surgery Registry, Central Clinical School, Monash University, Melbourne, Australia.
²⁹ Research Unit for Plastic Surgery, University of Southern Denmark and Odense University Hospital, Odense, Denmark.
³⁰ Lontoft, Nyhoj and Poulsen Plastic Surgery, Odense, Denmark.
³¹ Department of Upper Gastrointestinal and Bariatric Surgery, Musgrove Park Hospital, Taunton, UK.
³² Bariatric physician in Gastrobariatrica Santa Fe, Santa Fe, Mexico.
³³ Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.
³⁴ Department of Endocrine and Metabolic Surgery, CHU Lille, Univ Lille, Inserm, Institut Pasteur Lille, Lille, France.
³⁵ Department of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.
³⁶ Massachusetts General Hospital Weight Center, Harvard Medical School, Boston, Massachusetts, USA.
³⁷ Department of Surgery, Delta CHIREC Hospital, Brussels, Belgium.
³⁸ Department of Nutrition and Dietetics, North Tees and Hartlepool NHS Foundation Trust, Durham, UK.
³⁹ Dutch Association for Overweight and Obesity (NVOO), Amsterdam, The Netherlands.
⁴⁰ People Living with Obesity Representative, Kuwait City, Kuwait.
⁴¹ Patient Advocate, Trustee of The Obesity Empowerment Network, London, UK.
⁴² European Coalition for People Living with Obesity (ECPO), Dublin, Ireland.
⁴³ Irish Coalition for People Living with Obesity (ICPO), Kildare, Ireland.
⁴⁴ Obesity Action Coalition, Tampa, Florida, USA.
⁴⁵ Pacte Adiposité, The Belgian Foundation for the Rights of People living with obesity, Belgium.
⁴⁶ European Coalition for People Living with Obesity (ECPO), London, UK.
⁴⁷ Leeds Beckett University, Leeds, UK.
⁴⁸ People Living with Obesity Representative & Chair client council Dutch Obesity Clinic, Amsterdam, The Netherlands.
⁴⁹ KleinePorties, Kloetinge, The Netherlands.
⁵⁰ ConscienHealth, Obesity Action Coalition, Tampa, Florida, USA.
⁵¹ Adipositascirurgie Selbsthilfe Deutschland e.V. (Obesity Surgery Self-Help Organization), Mainz, Germany.
⁵² Obesity Canada, Edmonton, Canada.

PMID: 39419653
DOI: 10.1111/obr.13849

Abstract

The lack of standardization in patient-reported outcome measures (PROMs) has made measurement and comparison of quality of life (QoL) outcomes in research focused on obesity treatment challenging. This study reports on the results of the second and third global multidisciplinary Standardizing Quality of life measures in Obesity Treatment (S.Q.O.T.) consensus meetings, where a core set of PROMs to measure nine previously selected patient-reported outcomes (PROs) in obesity treatment research was established. The S.Q.O.T. II online and S.Q.O.T. III face-to-face hybrid consensus meetings were held in October 2021 and May 2022. The meetings were led by an independent moderator specializing in PRO measurement. Nominal group techniques, Delphi exercises, and anonymous voting were used to select the most suitable PROMs by consensus. The meetings were attended by 28 and 27 participants, respectively, including a geographically diverse selection of people living with obesity (PLWO) and experts from various disciplines. Out of 24 PROs and 16 PROMs identified in the first S.Q.O.T. consensus meeting, the following nine PROs and three PROMs were selected via consensus: BODY-Q (physical function, physical symptoms, psychological function, social function, eating behavior, and body image), IWQOL-Lite (self-esteem), and QOLOS (excess skin). No PROM was selected to measure stigma as existing PROMs deemed to be inadequate. A core set of PROMs to measure QoL in research focused on obesity treatment has been selected incorporating patients' and experts' opinions. This core set should serve as a minimum to use in obesity research studies and can be combined with clinical parameters.

Keywords: bariatric surgery; obesity treatment; patient‐reported outcome; quality of life.

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Abstract

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