Two Squaramide-Based Fluorescent Probes for Cu2+ and Cd2

Yuanwei Li; Hongxu Wang; Qian Tao; Bin Wang

doi:10.1007/s10895-024-03956-7

Two Squaramide-Based Fluorescent Probes for Cu²⁺ and Cd²

J Fluoresc. 2024 Oct 21. doi: 10.1007/s10895-024-03956-7. Online ahead of print.

Authors

Yuanwei Li^{1

2}, Hongxu Wang^{1

2}, Qian Tao^{1

2}, Bin Wang^{3

4}

Affiliations

¹ College of Chemistry and Chemical Engineering of China West Normal University, Nanchong, 637000, China.
² Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province of China, Nanchong, 637000, China.
³ College of Chemistry and Chemical Engineering of China West Normal University, Nanchong, 637000, China. [email protected].
⁴ Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province of China, Nanchong, 637000, China. [email protected].

PMID: 39432196
DOI: 10.1007/s10895-024-03956-7

Abstract

The development of potential toxic metal ion probes is of great significance in the field of environmental detection. Herein, two squaramide ligands (2a, 2b) were constructed by combining the characteristics of squaric acid and imine groups. 2a and 2b can recognize Cu²⁺ and Cd²⁺, with LOD of 1.26 × 10^-8 M and 2.04 × 10^-8 M, respectively, and have the advantages of fast response and wide pH range. The binding ratio and binding mode of the probe and the target ion were determined by Job's plot, ESI-MS, and ¹H NMR.

Keywords: Cd2+ detection; Cu2+ detection; Fluorescent probe; Squaramide.