Large B-Cell Lymphoma

Leyre Bento; Bertram Glass; Norbert Schmitz

doi:10.1007/978-3-031-44080-9_86

Large B-Cell Lymphoma

Review

In: The EBMT Handbook: Hematopoietic Cell Transplantation and Cellular Therapies [Internet]. 8th edition. Cham (CH): Springer; 2024. Chapter 86.

2024 Apr 11.

Authors

Leyre Bento¹, Bertram Glass², Norbert Schmitz³

Book Editors

Anna Sureda¹, Selim Corbacioglu², Raffaella Greco³, Nicolaus Kröger⁴, Enric Carreras⁵

Affiliations

¹ Department of Hematology, Son Espases University Hospital, IdISBa, University of Balearic Islands, Palma, Spain
² Department of Hematology and Stem Cell Therapy, Helios Hospital Berlin-Buch, Berlin, Germany
³ Department of Medicine A, Hematology, Oncology, Pneumonology and Hemostaseology, University Hospital Münster, Münster, Germany

Book Affiliations

¹ Hematology Department, Institut Català d'Oncologia - Hospital, Barcelona, Spain
² Department of Pediatric Hematology, Oncology and Stem Cell Transplantation University Medical Center, Regensburg, Germany
³ Hematology & Bone Marrow Transplantation, IRCCS San Raffaele Hospital, Milano, Italy
⁴ Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppend, Hamburg, Germany
⁵ Spanish Bone Marrow Donor Registry, Josep Carreras Foundation and Leukemia Research Institute, Catalunya, Barcelona, Spain

Auszug

The most recent WHO classification of tumors of hematopoietic and lymphoid tissues (Alaggio et al. 2022) classifies large B cell lymphomas (LBCL) into diffuse large B cell lymphoma (DLBCL) NOS with distinct morphological and molecular (germinal center B-cell, activated B-cell) subtypes, high-grade B-cell lymphomas (with MYC and BCL2 rearrangements or NOS subtype), and other less frequent subtypes.

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