Biocontrol Ability of Strain Bacillus amyloliquefaciens SQ-2 against Table Grape Rot Caused by Aspergillus tubingensis

J Agric Food Chem. 2024 Nov 6;72(44):24374-24386. doi: 10.1021/acs.jafc.4c04139. Epub 2024 Oct 22.

Abstract

Bacillus amyloliquefaciens strain SQ-2, isolated from a cured product, has been demonstrated to exhibit a highly efficacious performance against phytopathogens, including Stemphylium solani, Fusarium moniliforme, Fusarium graminearum, and Aspergillus tubingensis. In particular, with regard to A. tubingensis, which causes summer bunch rot, SQ-2 has been observed to suppress the mycelial growth of all tested grape cultivars by over 40%. Especially on Kyoho grapes, it has the highest inhibition rate of 53%. Scanning electron microscopy (SEM) confirms that SQ-2 is an effective agent for suppressing the mycelia proliferation, differentiation, and spore formation of A. tubingensis. Furthermore, an LC/MS analysis revealed that SQ-2 produces two principal lipopeptides, namely, bacillibactin and surfactin, in addition to a polyketide, bacillaene. Further analysis through gas chromatography-mass spectrometry (GC/MS) identified 41 distinct volatile organic compounds secreted by SQ-2. Transcriptomic analysis indicated that exposure to the metabolite of SQ-2 induced substantial gene expression alterations in A. tubingensis. These data suggest that B. amyloliquefaciens strain SQ-2 exhibits promising crop protection potential of inhibiting plant pathogens through the secretion of bacillibactin, surfactin, bacillaene, and VOCs.

Keywords: Bacillus amyloliquefaciens; VOCs; crop protection; secondary metabolites; transcriptomics analysis.

MeSH terms

  • Aspergillus* / chemistry
  • Aspergillus* / drug effects
  • Aspergillus* / genetics
  • Aspergillus* / growth & development
  • Aspergillus* / metabolism
  • Bacillus amyloliquefaciens* / chemistry
  • Bacillus amyloliquefaciens* / genetics
  • Bacillus amyloliquefaciens* / metabolism
  • Biological Control Agents / chemistry
  • Biological Control Agents / metabolism
  • Biological Control Agents / pharmacology
  • Gas Chromatography-Mass Spectrometry
  • Lipopeptides* / chemistry
  • Lipopeptides* / metabolism
  • Lipopeptides* / pharmacology
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / pharmacology
  • Plant Diseases* / microbiology
  • Plant Diseases* / prevention & control
  • Vitis* / chemistry
  • Vitis* / microbiology

Substances

  • Lipopeptides
  • Peptides, Cyclic
  • Biological Control Agents