We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog. Her eosinophilic enterocolitis was cured without relapse, and we were able to increase enteral nutrition. We found that teduglutide had an anti-inflammatory effect in this patient with eosinophilic gastrointestinal disease associated with short bowel syndrome. This report is the first to describe use of teduglutide in the treatment of eosinophilic gastrointestinal disease.
Keywords: eosinophilic gastrointestinal diseases; glucagon-like peptide-2 analog; immune effect; short bowel syndrome; teduglutide.
© 2024 Ogawa, Konishi, Tanaka, Takayasu, Uematsu, Ito, Takahashi and Kumamoto.