Racing through C. elegans mitosis using cyclin B3

J Cell Biol. 2024 Nov 4;223(11):e202410007. doi: 10.1083/jcb.202410007. Epub 2024 Oct 28.

Abstract

Racecar drivers use left-foot braking, i.e., simultaneously engaging brake and throttle, to carefully balance acceleration and traction when navigating chicanes. In this issue, Lara-Gonzalez et al. (https://doi.org/10.1083/jcb.202308034) show that C. elegans embryos employ the molecular equivalent of left-foot braking to faithfully speed through mitosis.

MeSH terms

  • Animals
  • Caenorhabditis elegans Proteins* / genetics
  • Caenorhabditis elegans Proteins* / metabolism
  • Caenorhabditis elegans* / genetics
  • Caenorhabditis elegans* / metabolism
  • Cyclin B / genetics
  • Cyclin B / metabolism
  • Mitosis*

Substances

  • Caenorhabditis elegans Proteins
  • Cyclin B