Recent Advances in the Development and Utilization of Nanoparticles for the Management of Malignant Solid Tumors

Cureus. 2024 Sep 27;16(9):e70312. doi: 10.7759/cureus.70312. eCollection 2024 Sep.

Abstract

The purpose of nanotechnology-based drug delivery systems or novel drug delivery systems is to improve the effectiveness of therapy, and their promising properties have led to their increasing significance in the management of cancer. The researchers have primarily focused on designing novel nanocarriers, like nanoparticles (NPs), that can effectively deliver drugs to target cells and respond specifically to conditions particular to cancer. Whether passive or active targeting, these nanocarriers can deliver therapeutic cargoes to the tumor site to release the drug from the drug delivery systems. The purpose of this study is to provide recent scientific literature and key findings to researchers as well as the scientific community from the medical and pharmaceutical domains by reporting current advancements in the development of NPs for the treatment of different malignant solid tumors, such as colorectal, pancreatic, prostate, and cervical cancer.

Keywords: cancer; drug delivery; malignant solid tumors; nanocarriers; nanoparticles; nanotechnology.

Publication types

  • Review