Invasive pulmonary aspergillosis is the most common type of pulmonary aspergillosis. This paper reported a patient with pulmonary aspergillosis secondary to obstructive pulmonary disease and other underlying diseases. The clinical manifestations included wheezing, cough, fever and wheezing rale in the lungs. Diagnosis was ultimately confirmed through pathogens targeted next generation sequencing and pathological examination of respiratory coughs. Following comprehensive treatment that included antifungal therapy, the patient was cured and discharged with a good prognosis.
侵袭性肺曲霉菌病是肺曲霉菌病最常见的类型。本文报道1例有阻塞性肺疾病等基础疾病的继发肺曲霉菌病病例，临床表现为喘息、咳嗽、发热及肺部广泛哮鸣音，通过病原靶向检测、呼吸道咳出物病理检查最终确诊，给予抗真菌等综合治疗后患者康复出院，预后良好。.
Keywords: Formaldehyde; Occupational toxic; Pulmonary aspergillosis; Pulmonary disease, chronic obstructive; Secondary; Toxic.