[Light chain amyloidosis with cuticular cysts as the initial symptom complicated with multiple myeloma: report of a case]

Q L Chen; Y Wang; H Q Chen; M Wang; S H Shao; W W Fu

doi:10.3760/cma.j.cn112151-20240511-00309

[Light chain amyloidosis with cuticular cysts as the initial symptom complicated with multiple myeloma: report of a case]

Zhonghua Bing Li Xue Za Zhi. 2024 Nov 8;53(11):1150-1152. doi: 10.3760/cma.j.cn112151-20240511-00309.

[Article in Chinese]

Authors

Q L Chen¹, Y Wang¹, H Q Chen², M Wang³, S H Shao¹, W W Fu¹

Affiliations

¹ Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao 266700, China.
² Department of Dermatology, the Affiliated Hospital of Qingdao University, Qingdao 266700, China.
³ Department of Cardiology, the Affiliated Hospital of Qingdao University, Qingdao 266700, China.

PMID: 39482058
DOI: 10.3760/cma.j.cn112151-20240511-00309

Abstract

系统性轻链型淀粉样变性是一种浆细胞疾病，淀粉样蛋白异常沉积于细胞外基质，造成沉积部位组织和器官损伤，可累及肾脏、心脏、肝脏、皮肤软组织、神经和肺等器官。本病预后不良，早诊早治至关重要，但因其临床表现多样，早期极易漏诊、误诊。本文报道1例以皮肤角质囊肿为首发症状的系统性轻链型淀粉样变性，并进行文献复习，以期提高临床、病理医师对此病的认识。.

Publication types

Case Reports

MeSH terms

Amyloidosis* / diagnosis
Amyloidosis* / metabolism
Amyloidosis* / pathology
Epidermal Cyst / metabolism
Epidermal Cyst / pathology
Female
Humans
Immunoglobulin Light Chains / metabolism
Immunoglobulin Light-chain Amyloidosis / diagnosis
Immunoglobulin Light-chain Amyloidosis / metabolism
Immunoglobulin Light-chain Amyloidosis / pathology
Male
Middle Aged
Multiple Myeloma* / complications
Multiple Myeloma* / diagnosis
Multiple Myeloma* / pathology

Substances

Immunoglobulin Light Chains