Fertility outcomes post immune checkpoint inhibitor exposure

Cancer Cell. 2024 Oct 23:S1535-6108(24)00391-X. doi: 10.1016/j.ccell.2024.10.005. Online ahead of print.

Abstract

Harrold et al. evaluate the fertility impact of checkpoint inhibitor blockade (ICB), demonstrating that unlike in utero exposure, post-exposure conception appears to result in uncomplicated pregnancies and healthy progeny. They demonstrate contemporaneous monitoring of temporal female hormonal fluctuations before, on, and post ICB exposure and prior to successful embryo implantation.

Publication types

  • Letter