Five potential allergens of freshwater crab (Somanniathelphusa sinensis), including hemocyanin, have been discovered. Specific IgE to haemocyanin was increased in crab-allergic than in crab-tolerant patients. The add-on of specific IgE to hemocyanin to skin prick test enhanced the specificity of the crab allergy diagnosis. IgE, immunoglobulin E; rHM, recombinant haemocyanin; sIgE, specific IgE; SPT: skin prick test.
Keywords: IgE; allergens and epitopes; hemocyanin; immunologic tests; shellfish allergy.
© 2024 John Wiley & Sons Ltd.