Home at last: Mixed signals guide memory T cells to residency

Kalle Liimatta; Elina I Zúñiga

doi:10.1016/j.immuni.2024.10.008

Home at last: Mixed signals guide memory T cells to residency

Immunity. 2024 Nov 12;57(11):2486-2488. doi: 10.1016/j.immuni.2024.10.008.

Authors

Kalle Liimatta¹, Elina I Zúñiga²

Affiliations

¹ Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
² Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA. Electronic address: [email protected].

PMID: 39536712
DOI: 10.1016/j.immuni.2024.10.008

Abstract

Tissue-resident memory T (T_RM) cells adapt to diverse environments, providing local long-term protection. In this issue of Immunity, Obers et al. and Raynor et al. demonstrate how diet, commensals, and host factors determine T_RM cell development, maintenance, and function across tissues.

Publication types

Kommentar

MeSH terms

Animals
Humans
Immunologic Memory* / immunology
Memory T Cells* / immunology
Signal Transduction / immunology