Phosphonomycin, a new antibiotic produced by strains of streptomyces

Science. 1969 Oct 3;166(3901):122-3. doi: 10.1126/science.166.3901.122.

Abstract

Phosphonomycin is a newly discovered antibiotic produced by streptomycetes. It is effective, when administered by the oral route, to mice infected with Gram-positive or Gram-negative microorganisms. The antibiotic is bactericidal and inhibits cell-wall synthesis.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / biosynthesis
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteria / drug effects
  • Cell Wall / drug effects
  • Infections / drug therapy*
  • Mice
  • Streptomyces / metabolism*

Substances

  • Anti-Bacterial Agents