Abstract
Primary systemic therapy with delayed surgical intervention has been employed for the treatment of malignant bone tumours since 1977 at the Universitäts-Kinderklinik and III. Medizinische Abteilung Graz. Improved therapeutic results, as originally reported on a large number of patients at the Memorial Sloan Kettering Cancer Center (MSKCC) seem to have been attained with a small group of patients (n = 5).
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adolescent
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Adult
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Antineoplastic Agents / therapeutic use*
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Bone Neoplasms / drug therapy*
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Bone Neoplasms / secondary
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Bone Neoplasms / surgery
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Child
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Drug Therapy, Combination
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Female
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Humans
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Male
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Methotrexate / therapeutic use
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Osteosarcoma / drug therapy*
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Osteosarcoma / secondary
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Osteosarcoma / surgery
Substances
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Antineoplastic Agents
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Methotrexate