Early complications and survival following short-term palliative radiotherapy in invasive bladder carcinoma

J Urol. 1996 Jan;155(1):100-2.

Abstract

Purpose: We studied the early side effects and survival rates after short-term radiotherapy (7 Gy. 3 times or 5 Gy. 4 times) in patients with muscle invasive bladder carcinoma.

Materials and methods: Between 1981 and 1992, 96 patients (median age 80 years) were treated. Followup was complete until 1994 or death.

Results: Early side effects caused the hospitalization of 22 patients and may have contributed to the death of 5 elderly patients. Median survival for patients with stages T2M0, T3M0, T4M0 and T2 to 4M+ disease was 27 months, 6.3 months, 5.6 months and 2.9 months, respectively.

Conclusions: Short-term radiotherapy is of doubtful benefit to elderly patients with advanced bladder carcinoma and may even be harmful.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / mortality*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / radiotherapy*
  • Carcinoma, Transitional Cell / mortality*
  • Carcinoma, Transitional Cell / pathology
  • Carcinoma, Transitional Cell / radiotherapy*
  • Female
  • Humans
  • Male
  • Neoplasm Invasiveness
  • Palliative Care*
  • Radiotherapy Dosage
  • Radiotherapy, High-Energy / adverse effects*
  • Survival Rate
  • Time Factors
  • Treatment Outcome
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms / mortality*
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / radiotherapy*