Anti-GOR antibodies in lichen planus

Dermatology. 1994;188(3):205-6. doi: 10.1159/000247140.

Abstract

Anti-GOR antibodies characterize patients with autoimmune hepatitis type 2 who are all positive for antibodies to hepatitis C virus (HCV) and have low titers of anti-liver/kidney-microsomal (LKM1) antibody. The documented prevalence of anti-HCV antibodies in patients with lichen planus (LP) and chronic liver disease (CLD) and their negativity for anti-LKM1 antibodies make them eligible for having anti-GOR antibodies. We studied such a possibility in 56 LP patients. Twenty of them had also CLD. Seven CLD patients without LP served as control. Overall, 11/63 patients had anti-GOR antibodies. All of them were anti-HCV positive and had CLD. CLD patients with LP showed the same prevalence of anti-GOR antibodies as CLD patients without LP.

MeSH terms

  • Adult
  • Aged
  • Autoantibodies / analysis*
  • Autoantibodies / immunology
  • Chronic Disease
  • Female
  • Hepatitis Antibodies / analysis*
  • Hepatitis Antibodies / immunology
  • Hepatitis C Antibodies
  • Humans
  • Kidney / immunology
  • Lichen Planus / complications
  • Lichen Planus / immunology*
  • Liver Diseases / complications
  • Liver Diseases / immunology*
  • Male
  • Microsomes, Liver / immunology
  • Middle Aged
  • Retrospective Studies

Substances

  • Autoantibodies
  • Hepatitis Antibodies
  • Hepatitis C Antibodies