The mniopetals, new inhibitors of reverse transcriptases from a Mniopetalum species (basidiomycetes). II. Structure elucidation

R Velten; D Klostermeyer; B Steffan; W Steglich; A Kuschel; T Anke

doi:10.7164/antibiotics.47.1017

The mniopetals, new inhibitors of reverse transcriptases from a Mniopetalum species (basidiomycetes). II. Structure elucidation

J Antibiot (Tokyo). 1994 Sep;47(9):1017-24. doi: 10.7164/antibiotics.47.1017.

Authors

R Velten¹, D Klostermeyer, B Steffan, W Steglich, A Kuschel, T Anke

Affiliation

¹ Department of Organic Chemistry, University of Munich, Germany.

PMID: 7523355
DOI: 10.7164/antibiotics.47.1017

Abstract

The structures of six new drimance sesquiterpenoids, mniopetals A-F, were elucidated by a combination of chemical and spectroscopic methods. The mniopetals are inhibitors of RNA-directed DNA-polymerases.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

4-Butyrolactone / analogs & derivatives*
4-Butyrolactone / chemistry
Basidiomycota / metabolism*
Magnetic Resonance Spectroscopy
Molecular Structure
Reverse Transcriptase Inhibitors*
Tetrahydronaphthalenes / chemistry*

Substances

Reverse Transcriptase Inhibitors
Tetrahydronaphthalenes
4-Butyrolactone