Hypokalaemic rhabdomyolysis: an unusual presentation of coeliac disease

Eur J Gastroenterol Hepatol. 1995 Feb;7(2):183-4.

Abstract

Objective: To describe the clinical presentation and management of a patient with hypokalaemic rhabdomyolysis secondary to coeliac disease.

Design: Retrospective study.

Setting: Hospital based.

Patient: A 60-year-old Caucasian man presenting with weakness caused by hypokalaemic rhabdomyolysis secondary to coeliac disease.

Interventions: Following the diagnosis by jejunal biopsy, the patient was treated with both intravenous and oral potassium supplements, and a gluten-free diet.

Outcome measures: Resolution of weakness and restitution of normal villous architecture following treatment.

Results: The patient's myopathy responded to the potassium supplements, his diarrhoea and histological changes resolved while on the gluten-free diet.

Conclusion: Patients with coeliac disease may present with hypokalaemia in association with steatorrhoea. If potassium loss is rapid, rhabdomyolysis may occur. Coeliac disease should be considered a cause of malabsorption-induced hypokalaemic rhabdomyolysis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Celiac Disease / complications*
  • Celiac Disease / therapy
  • Humans
  • Hypokalemia / etiology*
  • Hypokalemia / therapy
  • Male
  • Rhabdomyolysis / etiology*
  • Rhabdomyolysis / therapy