Abstract
Removal of low-density lipoproteins from plasma by dextran sulfate adsorption (DSA) in FH patients entails a decrease in plasma levels of thyroid hormones (-28.5% and -18.7%, respectively, for T3 and T4). This suggests that FH patients have a greater than normal fraction of thyroid hormones bound to lipoproteins, due to their expanded lipoprotein pool.
MeSH terms
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Adolescent
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Adult
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Blood Component Removal / methods*
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Dextran Sulfate*
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Female
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Humans
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Hyperlipoproteinemia Type II / blood
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Hyperlipoproteinemia Type II / therapy*
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Lipoproteins, LDL / blood
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Lipoproteins, LDL / isolation & purification*
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Male
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Middle Aged
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Thyroid Hormones / blood*
Substances
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Lipoproteins, LDL
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Thyroid Hormones
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Dextran Sulfate