Survival predictors in patients with a left ventricular ejection fraction of 10-30% receiving a coronary bypass: analysis of preoperative variables

Cardiovasc Surg. 1993 Oct;1(5):558-62.

Abstract

A total of 224 patients with angina pectoris and a left ventricular ejection fraction in the range of 10-30% (mean 24.2%) underwent coronary artery bypass grafting between April 1986 and August 1991. These patients received a mean (s.d.) of 2.9 (0.3) aortocoronary vein grafts. The overall operative mortality rate was 8.9%. The 1-, 2- and 3-year survival rates were 87.7%, 86.7% and 85.2%, respectively. Analysis of operative risk factors showed that patients with an end-diastolic left ventricular pressure > 24 mmHg were significantly more at risk (mortality rate 20.0%, P < 0.05) than those with an end-diastolic left ventricular pressure < or = 24 mmHg (mortality rate 6.2%). Patients with a perioperative cardiac index < 2.5 l min-1m-2 had higher mortality (25.4%) than those with a cardiac index > or = 2.5 l min-1m-2 (mortality 1.9%, P < 0.001). The operative mortality rate of patients with a cardiac index < 2.5 l min-1m-2 and an end-diastolic left ventricular pressure > 24 mmHg was 40.5%. Patients with a left ventricular ejection fraction of 10-20% were not significantly more at risk (P > 0.05) than those with a left ventricular ejection fraction of 21-30%.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angina Pectoris / mortality
  • Angina Pectoris / physiopathology
  • Angina Pectoris / surgery
  • Angina, Unstable / mortality
  • Angina, Unstable / physiopathology
  • Angina, Unstable / surgery
  • Cardiac Output, Low / mortality
  • Cardiac Output, Low / physiopathology
  • Cardiac Output, Low / surgery*
  • Cause of Death
  • Coronary Artery Bypass*
  • Coronary Disease / mortality
  • Coronary Disease / physiopathology
  • Coronary Disease / surgery*
  • Female
  • Follow-Up Studies
  • Hemodynamics / physiology*
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / mortality
  • Myocardial Infarction / physiopathology
  • Myocardial Infarction / surgery
  • Postoperative Complications / mortality*
  • Postoperative Complications / physiopathology
  • Prospective Studies
  • Risk Factors
  • Survival Rate
  • Ventricular Function, Left / physiology