[Simultaneous occurrence of lupus anticoagulant and acquired "storage pool" disease of thrombocytes]

Orv Hetil. 1994 May 8;135(19):1031-4.
[Article in Hungarian]

Abstract

The authors describe the case of a female patient with a history of simultaneous abortion and deep vein thrombosis as well as moderate bleeding disturbances. Investigations revealed the presence of lupus anticoagulant while a thrombocyte "storage pool" disease was confirmed. This case demonstrates the association of these two haemostatic disturbances, and points to a possible relationship between them. Since detailed analyses failed to demonstrate the presence of antiplatelet antibodies, the authors suggest a possible damaging effect of lupus anticoagulant to the endothelium leading to thrombocyte activation.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Abortion, Spontaneous
  • Adult
  • Antiphospholipid Syndrome / complications
  • Antiphospholipid Syndrome / immunology*
  • Dilatation and Curettage
  • Female
  • Glomerulonephritis, IGA / complications
  • Glomerulonephritis, IGA / immunology*
  • Humans
  • Lupus Coagulation Inhibitor / immunology*
  • Platelet Aggregation
  • Platelet Storage Pool Deficiency / complications
  • Platelet Storage Pool Deficiency / immunology*
  • Pregnancy

Substances

  • Lupus Coagulation Inhibitor