Lectin histochemistry of cell-surface glycoconjugates in the primary olfactory projections of the newt

Cell Mol Biol (Noisy-le-grand). 1993 Sep;39(6):651-8.

Abstract

The binding of 14 lectins were performed on paraffin-embedded sections of the olfactory bulb of Triturus to identify specific glycoconjugates on the cell surface of primary olfactory projections. The histochemical lectin staining patterns indicate that the membrane of olfactory neurons terminating in the main olfactory bulb contained prevalently oligosaccharides with alpha-acetyl-D-galactosamine as terminal residues. In the accessory olfactory bulb, instead, the primary olfactory projections possess a high density of alpha-D-galactose as sugar residues. The selective lectin binding on the surface of primary olfactory axons suggests that specific cell surface glycoproteins may have a role in the axonal growth due to the continual cycle of proliferation and death of olfactory receptors.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Axons / chemistry
  • Carbohydrate Sequence
  • Glycoconjugates / analysis*
  • Glycoconjugates / metabolism
  • Lectins / metabolism*
  • Molecular Sequence Data
  • Olfactory Bulb / anatomy & histology
  • Olfactory Bulb / chemistry*
  • Olfactory Nerve / chemistry
  • Oligosaccharides / analysis
  • Sensory Receptor Cells / chemistry*
  • Triturus / metabolism*

Substances

  • Glycoconjugates
  • Lectins
  • Oligosaccharides