The widespread availability of neuroimaging tests and the increasing use of stereotactic biopsy or surgical resection to obtain a histologic diagnosis have resulted in more patients with uncommon brain tumors coming to the attention of doctors. This article reviews the presentation and management of some of the less common brain tumors in adults. These include pineal tumors, medulloblastomas, ependymomas, choroid plexus tumors, ganglion cell tumors, neurocytomas, dysembryoplastic neuroepithelial tumors, esthesioneuroblastomas, Lhermitte-Duclos disease, hemangioblastomas, chordomas, and cystic lesions.