Preliminary evaluation of fluid-attenuated inversion-recovery MR in the diagnosis of intracranial tumors

AJNR Am J Neuroradiol. 1996 Jun-Jul;17(6):1081-6.

Abstract

Purpose: To report our preliminary results in the application of a turbo fluid-attenuated inversion-recovery (FLAIR) MR technique to the diagnosis of intracranial tumors and to assess the clinical usefulness of this technique.

Methods: Thirty-four patients with various intracranial tumors were studies with MR imaging, including a turbo FLAIR sequence. FLAIR images were compared with images obtained with conventional spin-echo sequences.

Results: Except for 2 lesions in 1 patients, tumor signal intensities on FLAIR images were consistent with those shown on T2-weighted spin-echo images. FLAIR images showed peritumoral edema more clearly than T2-Weighted and proton density-weighted images when the tumor itself was not hyperintense. In 8 of 23 patients in whom edema was associated with tumor, FLAIR images provided better definition between edema and tumor than did T2-weighted and proton density-weighted images. In 5 patients, FLAIR images depicted different signal intensity between cerebrospinal fluid and a cystic or necrotic component. In 20 of 22 patients, postcontrast FLAIR images showed contrast enhancement comparable to that seen on postcontrast T1-weighted images.

Conclusion: Turbo FLAIR images can supplement conventional spin-echo images in the diagnosis of intracranial tumors.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Edema / diagnosis
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / secondary
  • Child
  • Contrast Media
  • Drug Combinations
  • Female
  • Gadolinium DTPA
  • Glioma / diagnosis
  • Humans
  • Image Processing, Computer-Assisted / instrumentation*
  • Magnetic Resonance Imaging / instrumentation*
  • Male
  • Meglumine
  • Meningeal Neoplasms / diagnosis
  • Meningioma / diagnosis
  • Middle Aged
  • Neuroma, Acoustic / diagnosis
  • Organometallic Compounds
  • Pentetic Acid / analogs & derivatives

Substances

  • Contrast Media
  • Drug Combinations
  • Organometallic Compounds
  • Meglumine
  • Pentetic Acid
  • Gadolinium DTPA