Mechanism of action of camptothecin

Ann N Y Acad Sci. 1996 Dec 13:803:44-9. doi: 10.1111/j.1749-6632.1996.tb26375.x.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Camptothecin / pharmacology*
  • Cell Death
  • Cell Division
  • DNA / drug effects
  • DNA Topoisomerases, Type I / drug effects
  • DNA Topoisomerases, Type I / metabolism
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Models, Chemical
  • S Phase
  • Transcription, Genetic
  • Ubiquitins / drug effects
  • Ubiquitins / metabolism

Substances

  • Antineoplastic Agents, Phytogenic
  • Enzyme Inhibitors
  • Ubiquitins
  • DNA
  • DNA Topoisomerases, Type I
  • Camptothecin