Mutations within the CD4-CDR-3-like loop allow replication in an immortalized T cell line of HIV type 1 viruses chimeric for envelope glycoproteins containing non-syncytium-inducing V3 loops

AIDS Res Hum Retroviruses. 1997 Jan 20;13(2):121-3. doi: 10.1089/aid.1997.13.121.
No abstract available

Publication types

  • Letter

MeSH terms

  • Amino Acid Sequence
  • CD4 Antigens / genetics*
  • Cell Line
  • Giant Cells / virology
  • HIV Envelope Protein gp120 / chemistry
  • HIV Envelope Protein gp120 / genetics*
  • HIV Envelope Protein gp120 / immunology
  • HIV-1 / genetics
  • HIV-1 / immunology
  • HIV-1 / physiology*
  • Humans
  • Molecular Sequence Data
  • Mutagenesis, Site-Directed
  • Peptide Fragments / chemistry
  • Peptide Fragments / genetics*
  • Peptide Fragments / immunology
  • Reassortant Viruses / genetics
  • Reassortant Viruses / physiology
  • Species Specificity
  • T-Lymphocytes / cytology
  • T-Lymphocytes / virology*
  • Virus Replication

Substances

  • CD4 Antigens
  • HIV Envelope Protein gp120
  • HIV envelope protein gp120 (305-321)
  • Peptide Fragments