Carney complex: report of a kindred with predominantly cutaneous manifestations

D K Armstrong; A D Irvine; J M Handley; M Y Walsh; D R Hadden; E A Bingham

Carney complex: report of a kindred with predominantly cutaneous manifestations

Br J Dermatol. 1997 Apr;136(4):578-82.

Authors

D K Armstrong¹, A D Irvine, J M Handley, M Y Walsh, D R Hadden, E A Bingham

Affiliation

¹ Department of Dermatology, Royal Victoria Hospital, Belfast, Northern Ireland.

PMID: 9155962

Abstract

We report a four-generation kindred with the complex of myxomas, spotty pigmentation and endocrine overactivity. This kindred demonstrates a relatively limited phenotypic expression with predominance of cutaneous features. Male-to-male transmission confirms the autosomal dominant nature of the condition. We propose that pilonidal sinus may be an associated manifestation in this kindred.

Publication types

Case Reports

MeSH terms

Adult
Breast Neoplasms / genetics*
Breast Neoplasms / pathology
Child, Preschool
Facial Dermatoses / genetics*
Facial Dermatoses / pathology
Female
Fibroadenoma / genetics*
Fibroadenoma / pathology
Humans
Male
Middle Aged
Neoplastic Syndromes, Hereditary / genetics*
Neoplastic Syndromes, Hereditary / pathology
Pedigree
Pigmentation Disorders / genetics*
Pigmentation Disorders / pathology
Syndrome