Pica and the obsessive-compulsive spectrum disorders

S Afr Med J. 1996 Dec;86(12 Suppl):1586-8, 1591-2.

Abstract

Background: The concept of a spectrum of obsessive-compulsive related disorders may have clinical and research heuristic value in the approach to disorders similar to obsessive-compulsive disorder (OCD) in respect of phenomenology and psychobiology. Like other repetitive and ritualistic behaviours, pica may be postulated to fall at times on this spectrum.

Methods: Five cases of pica seen at our clinics are presented here in order to test this hypothesis. Phenomenology, neurobiology (where available) and pharmacotherapy data are provided in order to consider a possible relationship with OCD and OCD spectrum disorders.

Results: In 2 of the cases, pica appeared to be a compulsion and patients had additional symptoms which met diagnostic criteria for OCD. In 2 of the cases, the clinical picture and neurobiological data were reminiscent of an impulse control disorder. Four of the 5 patients responded to treatment with a serotonin re-uptake inhibitor (SRI).

Conclusion: These results are consistent with a hypothesis that at least some cases of pica may usefully be conceptualised as lying within a compulsive-impulsive spectrum of symptoms and disorders.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 1-Naphthylamine / analogs & derivatives
  • 1-Naphthylamine / therapeutic use
  • Adolescent
  • Adult
  • Antidepressive Agents / therapeutic use
  • Child
  • Citalopram / therapeutic use
  • Clomipramine / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / complications*
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / drug therapy
  • Pica / complications*
  • Pica / diagnosis
  • Pica / drug therapy
  • Sertraline
  • Tomography, Emission-Computed, Single-Photon

Substances

  • Antidepressive Agents
  • Citalopram
  • 1-Naphthylamine
  • Clomipramine
  • Sertraline